China Factory Iodomethane CAS No.:74-88-4
Iodomethane Basic information
| Product Name: | Iodomethane |
| Synonyms: | IODOMETHANESYNONYMS/METHYLIODIDE;METHYLIODIDE,REAGENT;10domethane;CH3I;Halon 10001;Iodomethane,99.5%;Iodomethane, 2M solution in tert-butyl methyl ether;Iodomethane, stabilized, 99% |
| CAS: | 74-88-4 |
| MF: | CH3I |
| MW: | 141.94 |
| EINECS: | 200-819-5 |
| Product Categories: | IOD – Iodomethane;β;Alkyl;Analytical Enzymes;and Substrates;Biochemicals and Reagents;Organics;Piperazine derivates;Building Blocks;Chemical Synthesis;Enzymes;-Glucuronidase;-Glucuronidase Drug Analysis Bundle;Halogenated Hydrocarbons;Inhibitors;Organic Building Blocks;Agro-Products, Miscellaneous Reagents;Pharma;Solvent |
Iodomethane Chemical Properties
| Melting point | −64(lit.) |
| Boiling point | 41-43 °C |
| density | 2.28 g/mL at 25 °C(lit.) |
| vapor density | 4.89 (vs air) |
| vapor pressure | 24.09 psi ( 55 °C) |
| refractive index | n20/D 1.530 |
| Fp | −18 °F |
| storage temp. | 2-8°C |
| solubility | water: soluble14g/L at 20°C |
| form | Liquid |
| Specific Gravity | 2.280 |
| color | Clear |
| Odor | Sweet, ethereal odor (no threshold data available); inadequate warning properties |
| PH | 5.2 (H2O, 25ºC) |
| Water Solubility | 14 g/L (20 ºC) |
| Sensitive | Light Sensitive |
| Merck | 14,6087 |
| BRN | 969135 |
| Henry’s Law Constant | 5.06 at 21 °C (Gan and Yates, 1996) |
| Exposure limits | TLV-TWA 2 ppm (~11 mg/m3) (ACGIH), 5 ppm (MSHA and OSHA); carcinogenicity: Animal Limited Evidence (IARC), Suspected Human Carcinogen. |
| CAS DataBase Reference | 74-88-4(CAS DataBase Reference) |
| IARC | 3 (Vol. 41, Sup 7, 71) 1999 |
| NIST Chemistry Reference | Methyl iodide(74-88-4) |
| EPA Substance Registry System | Methyl iodide (74-88-4) |
Iodomethane Usage
Uses Methyl iodide is used in the analysis of pyridine; microscopy; as an embedding materialfor examining diatoms (Merck 1996); and asa methylating agent.
Uses .Iodomethane is an approved pesticide used to control insects, plant parasitic nematodes, soil borne pathogens and weed seeds.
Uses Methylating agent; in microscopy because of its high refractive index; as imbedding material for examining diatoms; in testing for pyridine. Light sensitive etching agent for electronic circuits; component in fire extinguishers.
Iodomethane Application
Iodomethane is a useful methylating agent that mediates the alkylation of carbon, oxygen, sulfur, nitrogen and phosphorus nucleophiles[9, 10]. For example, phenol reacts with methyl iodide to give anisole. In the Monsanto process, the in situ formed iodomethane reacts with carbon monoxide in the presence of a rhodium complex to give acetyl iodide, which on hydrolysis yields acetic acid[11]. It reacts with magnesium to form the Grignard reagent, methyl-magnesium iodide used in organic synthesis[12]. It also finds applications as an intermediate in the manufacture of pharmaceuticals and in phase-transfer catalysts.
Methyl iodide can also be used as a kind of pesticide used to control insects, plant parasitic nematodes, soil borne pathogens, and weed seeds in vegetables. It can be used in the field growing strawberries, peppers, nut crops, tomatoes, grape vines, ornamentals and turf and nursery growing strawberries, stone fruits, tree nuts, and conifer trees. Its fumigant action is thought to be via the nucleophilic displacement(SN2) reaction in various amino acids and peptides within target organisms. It can also be used as a fire extinguisher[4, 5, 13, 14].
